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triphosphopyridine nucleotide

beta-nicotinamide adenine dinucleotide phosphoric acid

CAS: 53-59-8

Molecular Formula: C21H28N7O17P3

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triphosphopyridine nucleotide - Names and Identifiers

Name beta-nicotinamide adenine dinucleotide phosphoric acid
Synonyms TPN
NADP
TPNH
coenzyme II
nadide phosphate
TRIPHOSPHOPYRIDINE NUCLEOTIDE
triphosphopyridine nucleotide
Nicotinamide-adenine dinucleotide phosphate
B-NICOTINAMIDEADENINEDINUCLEOTIDEPHOSPHATE,HYDRATE
B-NICOTINAMIDE ADENINE DINUCLEOTIDE*PHOS PHATE FREE
β-nicotinamide adenine dinucleotide phosphate hydrate
beta-nicotinamide adenine dinucleotide phosphoric acid
[(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-[[[[(2R,3S,4R,5R)-5-(5-carbamoylpyridin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-4-hydroxy-oxolan-3-yl]oxyphosphonic acid
[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphate
[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxy-tetrahydrofuran-2-yl]methyl [[(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] hydrogen phosphate
CAS 53-59-8
EINECS 200-178-1
InChI InChI=1/C21H28N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39)/p+1/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

triphosphopyridine nucleotide - Physico-chemical Properties

Molecular FormulaC21H28N7O17P3
Molar Mass743.41
Solubility H2O: 50mg/mL, clear, slightly yellow
Appearancepowder to crystal
ColorWhite to Orange to Green
Maximum wavelength(λmax)['260nm(lit.)']
Merck14,6348
pKapKa1 3.9; pKa2 6.1(at 25℃)
Storage ConditionKeep in dark place,Inert atmosphere,Store in freezer, under -20°C
MDLMFCD10567218
Physical and Chemical PropertiesWhite or off-white powder, easy hygroscopic deliquescence. pKa{1}= 3.9;pKa{2}= 6.1. Soluble in water, methanol, difficult to dissolve in ethanol, insoluble in ether and ethyl acetate.

triphosphopyridine nucleotide - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
WGK Germany3
RTECSUU3440000
FLUKA BRAND F CODES10-21

triphosphopyridine nucleotide - Reference

Reference
Show more
1. Jiang Yi, Jia Xiaohui, Li Peining, etc. Detection of mutagenicity of five kinds of plastic track surface extracts by Ames test [J]. Canceration · aberration · mutation, 2017(4).
2. Zhu Lijuan, Hu Die, storage of Yaqin, etc. Preparation of chiral compound (S)-styrene oxide by multi-enzyme coupling catalysis [J]. Journal of Food and Biotechnology, 2017, 36(5):473-478.
3. Tang, Yanping, et al.. Plant Physiology and Biochemistry 112 (2017): 19-28.https:// doi.org/10.1016/j. Plashy.2016.1
4. Jia et al Hao-Yu [IF = 5.221]. "Engineering prospective alcosol Dehydrogenase Activity of a Reductive Aminase for Selective Reduction of bio-based Furans." Front Chem. 2021; 9: 610091
5. [IF = 5.192] Wei Li et al."Risk prediction of drug-drug interaction potential of phenetin and miconazole topical formulations." Chem-Biol. 2021 Jul;343:109498
Note: For some products, we can only provide some information, we do not guarantee the authority of the information provided, only for customers Study on the use of exchange.
purpose: Biochemical Study.
storage conditions: 2-8℃
sensitivity: highly hygroscopic
solubility: soluble in water and methanol. Less soluble in ethanol, almost insoluble in ethyl ether and ethyl acetate
Introduction: Is the coenzyme of dehydrogenase and hydrogenation enzymes.
Properties: white or light yellow powder or solid.
The maximum absorption wavelength was 260nm (δ18000).

triphosphopyridine nucleotide - Reference Information

EPA chemical information Information provided by: ofmpub.epa.gov (external link)
Biological activity NADP is nicotinamide adenine dinucleotide phosphate, which is alternately oxidized (NADP) and reduced (NADPH) as a key factor in the metabolism of all organisms.
use is an essential coenzyme in organisms for biochemical and drug research.
Biochemical research.
production method fresh sheep liver is prepared by grinding and filtering treatment, hot water extraction at 80 ℃, trichloroacetic acid treatment, alkali neutralization to pH5-6, centrifugal precipitation washing, crude product purification, cation exchange resin replacement, shaving elution, refining and drying.
Last Update:2024-04-09 20:52:54
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